The action of DNA topoisomerase II (Top2) creates transient DNA breaks that are normally concealed inside Top2-DNA covalent complexes. Top2 pois...
May 1, 2017 -Studies from Dr. Feng Shao’s laboratory discover that caspase-3 can cleave GSDME to trigger pyroptosis which contributes to the toxic ...
‑ PathologicalAfter cellular high throughput screen, the authors selected compound 1, which had a The PTN graduate student Li Li from Dr. Zhiyuan ...
Discovery of a new class of highly potent necroptosis affected targeting the mixed lineage kinase domain-like protein” RIP1,Necroptosis is one of the i...
Jan. 31, 2017 – Dr. Ting Chen of NIBS, Beijing published a research article online entitled “Efficient in vivo gene editing using ribonucleopr...