Dr. Wenhui Li 's lab published a review describes the latest research and drug discovery of HBV and HDV.

    On Sept. 6, 2015, Dr. Wenhui Li 's lab published a review titled " NTCP opens the door for hepatitis B virus infection" on Antiviral Research.

    A liver bile acids transporter, sodium taurocholate cotransporting polypeptide (NTCP, encoded by SLC10A1) was recently identified as a functional receptor for hepatitis B virus (HBV) and its satellite hepatitis D virus (HDV). NTCP-complemented human hepatoma HepG2 cells (HepG2-NTCP) were shown to support infection of HBV and HDV in vitro, providing a much-needed and convenient cell culture system for the viruses. Identification of NTCP as a functional receptor for HBV has significantly advanced our understanding of the viral life cycle and opened new opportunities for developing anti-HBV interventions. This article forms part of a symposium in Antiviral Research on "An unfinished story: from the discovery of the Australia antigen to the development of new curative therapies for hepatitis B".

http://www.sciencedirect.com/science/article/pii/S0166354215001333