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科学研究

2018

Original Research Articles

  1. Zhou, Yu, Wang, Yuanxun, Li, Pengfei, Huang, Xi-Ping, Qi, Xiangbin, Du, Yunfei* & Huang, Niu*. Exploring Halogen Bonds in 5-Hydroxytryptamine 2B Receptor-Ligand Interactions. ACS Med Chem Lett 9, 1019-1024, doi:10.1021/acsmedchemlett.8b00300 (2018).


  2. Zhou, Ping, She, Yang, Dong, Na, Li, Peng, He, Huabin, Borio, Alessio, Wu, Qingcui, Lu, Shan, Ding, Xiaojun, Cao, Yong, Xu, Yue, Gao, Wenqing, Dong, Mengqiu, Ding, Jingjin, Wang, Da-Cheng, Zamyatina, Alla & Shao, Feng*. Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose. Nature 561, 122-126, doi:10.1038/s41586-018-0433-3 (2018).


  3. Zhou, Jin-Xing, Liu, Zhang-Wei, Li, Yong-Qiang, Li, Lin, Wang, Bangjun, Chen, She & He, Xin-Jian*. Arabidopsis PWWP domain proteins mediate H3K27 trimethylation on FLC and regulate flowering time. J Integr Plant Biol 60, 362-368, doi:10.1111/jipb.12630 (2018).


  4. Zhao, Yue, Shi, Jianjin & Shao, Feng*. in Methods Mol Biol Vol. 1714 131-148 (2018).


  5. Zhao, Qiu-Yuan & He, Xin-Jian*. Exploring potential roles for the interaction of MOM1 with SUMO and the SUMO E3 ligase-like protein PIAL2 in transcriptional silencing. PLoS One 13, e0202137, doi:10.1371/journal.pone.0202137 (2018).


  6. Zhao, Haifang, Wang, Jing & Wang, Tao*. The V-ATPase V1 subunit A1 is required for rhodopsin anterograde trafficking in Drosophila. Mol Biol Cell 29, 1640-1651, doi:10.1091/mbc.E17-09-0546 (2018).


  7. Zhang, Yanping, Zhang, Wenhong & Dong, Mengqiu*. The miR-58 microRNA family is regulated by insulin signaling and contributes to lifespan regulation in Caenorhabditis elegans. Sci China Life Sci 61, 1060-1070, doi:10.1007/s11427-018-9308-8 (2018).


  8. Zhang, Xiao-Ran, He, Jia-Bei, Wang, Yi-Zheng & Du, Li-Lin*. A Cloning-Free Method for CRISPR/Cas9-Mediated Genome Editing in Fission Yeast. G3 (Bethesda) 8, 2067-2077, doi:10.1534/g3.118.200164 (2018).


  9. Zhang, X. R., He, J. B., Wang, Y. Z. & Du, L. L. A Cloning-Free Method for CRISPR/Cas9-Mediated Genome Editing in Fission Yeast. G3 (Bethesda) 8, 2067-2077, doi:10.1534/g3.118.200164 (2018).


  10. Zhang, Xiaoyun#, Wang, Jian-Hua#, Tan, Dan, Li, Qiang, Li, Maodong, Gong, Zhou, Tang, Chun, Liu, Zhirong, Dong, Meng-Qiu* & Lei, Xiaoguang*. Carboxylate-Selective Chemical Cross-Linkers for Mass Spectrometric Analysis of Protein Structures. Anal Chem 90, 1195-1201, doi:10.1021/acs.analchem.7b03789 (2018).


  11. Zhang, Xuekai, Lu, Gang, Sun, Meng, Mahankali, Madhu, Ma, Yanfei, Zhang, Mingming, Hua, Wangde, Hu, Yuting, Wang, Qingbing, Chen, Jinghuo, He, Gang*, Qi, Xiangbing*, Shen, Weijun*, Liu, Peng* & Chen, Gong*. A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp(3) C-H arylation. Nat Chem 10, 540-548, doi:10.1038/s41557-018-0006-y (2018).


  12. Zhang, Hongjuan, Zhan, Cheng, Ke, Ji, Xue, Zhiqiang, Zhang, Aiqun, Xu, Kaifeng, Shen, Zhirong, Yu, Lei & Chen, Liang*. Correction: EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment. Oncotarget 9, 35285, doi:10.18632/oncotarget.26255 (2018).


  13. Zhang, Hongjuan, Cao, Jing, Li, Lin, Liu, Yanbin, Zhao, Hong, Li, Nan, Li, Bo, Zhang, Aiqun, Huang, Huanwei, Chen, She, Dong, Mengqiu, Yu, Lei, Zhang, Jian* & Chen, Liang*. Author Correction: Identification of urine protein biomarkers with the potential for early detection of lung cancer. Sci Rep 8, 14486, doi:10.1038/s41598-018-32183-x (2018).


  14. Zhan, Cheng*. POMC Neurons: Feeding, Energy Metabolism, and Beyond. Adv Exp Med Biol 1090, 17-29, doi:10.1007/978-981-13-1286-1_2 (2018).


  15. Yu, Zhou, Jiang, Kaiju, Xu, Zijian, Huang, Huanwei, Qian, Nannan, Lu, Zhiwei, Chen, Daoming, Di, Ruonan, Yuan, Tianyi, Du, Zhenhai, Xie, Wei, Lu, Xiaoling, Li, Huawei, Chai, Renjie, Yang, Yong, Zhu, Bing, Kunieda, Tetsuo, Wang, Fengchao* & Chen, Ting*. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. Cell Stem Cell 23, 487-500 e486, doi:10.1016/j.stem.2018.07.016 (2018).


  16. Ying, Zhengxin, Pan, Chenjie, Shao, Tianyu, Liu, Liqing, Li, Lin, Guo, Dejia, Zhang, Sitao, Yuan, Tianyi, Cao, Ran, Jiang, Zhaodi, Chen, She, Wang, Fengchao & Wang, Xiaodong*. Mixed Lineage Kinase Domain-like Protein MLKL Breaks Down Myelin following Nerve Injury. Mol Cell 72, 457-468 e455, doi:10.1016/j.molcel.2018.09.011 (2018).


  17. Yin, Chang & Xi, Rongwen*. A Phyllopod-Mediated Feedback Loop Promotes Intestinal Stem Cell Enteroendocrine Commitment in Drosophila. Stem Cell Reports 10, 43-57, doi:10.1016/j.stemcr.2017.11.014 (2018).


  18. Yang, Jingyi, Zhao, Yue, Li, Peng, Yang, Yi, Zhang, Ejuan, Zhong, Maohua, Li, Yaoming, Zhou, Dihan, Cao, Yuan, Lu, Mengji, Shao, Feng* & Yan, Huimin*. Sequence determinants of specific pattern-recognition of bacterial ligands by the NAIP-NLRC4 inflammasome. Cell Discov 4, 22, doi:10.1038/s41421-018-0018-1 (2018).


  19. Wu, Xi*, Li, Lanlan & Jiang, Hui*. Mitochondrial inner-membrane protease Yme1 degrades outer-membrane proteins Tom22 and Om45. J Cell Biol 217, 139-149, doi:10.1083/jcb.201702125 (2018).


  20. Wei, Chao, Han, Xiao, Weng, Danwei, Feng, Qiru, Qi, Xiangbing, Li, Jin* & Luo, Minmin*. Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA. Cell Discov 4, 60, doi:10.1038/s41421-018-0060-z (2018).


  21. Wang, Zhiqiang, Ma, Jing, Miyoshi, Chika, Li, Yuxin, Sato, Makito, Ogawa, Yukino, Lou, Tingting, Ma, Chengyuan, Gao, Xue, Lee, Chiyu, Fujiyama, Tomoyuki, Yang, Xiaojie, Zhou, Shuang, Hotta-Hirashima, Noriko, Klewe-Nebenius, Daniela, Ikkyu, Aya, Kakizaki, Miyo, Kanno, Satomi, Cao, Liqin, Takahashi, Satoru, Peng, Junmin, Yu, Yonghao, Funato, Hiromasa*, Yanagisawa, Masashi* & Liu, Qinghua*. Quantitative phosphoproteomic analysis of the molecular substrates of sleep need. Nature 558, 435-439, doi:10.1038/s41586-018-0218-8 (2018).


  22. Wang, Yanjie, Tang, Zan, Huang, Huanwei, Li, Jiao, Wang, Zheng, Yu, Yuanyuan, Zhang, Chengwei, Li, Juan, Dai, Huaping, Wang, Fengchao, Cai, Tao* & Tang, Nan*. Pulmonary alveolar type I cell population consists of two distinct subtypes that differ in cell fate. Proc Natl Acad Sci U S A 115, 2407-2412, doi:10.1073/pnas.1719474115 (2018).


  23. Wang, Yuanxun, Du, Yunfei* & Huang, Niu*. A survey of the role of nitrile groups in protein-ligand interactions. Future Med Chem 10, 2713-2728, doi:10.4155/fmc-2018-0252 (2018).


  24. Wang, Yibing, Cao, Liqin, Lee, Chia-Ying, Matsuo, Tomohiko, Wu, Kejia, Asher, Greg, Tang, Lijun, Saitoh, Tsuyoshi, Russell, Jamie, Klewe-Nebenius, Daniela, Wang, Li, Soya, Shingo, Hasegawa, Emi, Cherasse, Yoan, Zhou, Jiamin, Li, Yuwenbin, Wang, Tao, Zhan, Xiaowei, Miyoshi, Chika, Irukayama, Yoko, Cao, Jie, Meeks, Julian P, Gautron, Laurent, Wang, Zhiqiang, Sakurai, Katsuyasu, Funato, Hiromasa, Sakurai, Takeshi, Yanagisawa, Masashi, Nagase, Hiroshi, Kobayakawa, Reiko, Kobayakawa, Ko*, Beutler, Bruce* & Liu, Qinghua*. Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors. Nat Commun 9, 2041, doi:10.1038/s41467-018-04324-3 (2018).


  25. Tang, Zan, Hu, Yucheng, Wang, Zheng, Jiang, Kewu, Zhan, Cheng, Marshall, Wallace F* & Tang, Nan*. Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis. Dev Cell 44, 313-325 e315, doi:10.1016/j.devcel.2017.12.013 (2018).


  26. Tan, Lian-Mei, Zhang, Cui-Jun, Hou, Xiao-Mei, Shao, Chang-Rong, Lu, Yu-Jia, Zhou, Jin-Xing, Li, Yong-Qiang, Li, Lin, Chen, She & He, Xin-Jian*. The PEAT protein complexes are required for histone deacetylation and heterochromatin silencing. EMBO J 37, doi:10.15252/embj.201798770 (2018).


  27. Shang, Congping, Chen, Zijun, Liu, Aixue, Li, Yang, Zhang, Jiajing, Qu, Baole, Yan, Fei, Zhang, Yaning, Liu, Weixiu, Liu, Zhihui, Guo, Xiaofei, Li, Dapeng, Wang, Yi & Cao, Peng*. Divergent midbrain circuits orchestrate escape and freezing responses to looming stimuli in mice. Nat Commun 9, 1232, doi:10.1038/s41467-018-03580-7 (2018).


  28. Schroder, Kate*, Kanneganti, Thirumala-Devi*, Shao, Feng* & Broz, Petr*. Mechanisms and Consequences of Inflammasome Activation. J Mol Biol 430, 131-132, doi:10.1016/j.jmb.2017.12.005 (2018).


  29. Ren, Suxia, Huang, Zengyi, Jiang, Yuqiang & Wang, Tao*. dTBC1D7 regulates systemic growth independently of TSC through insulin signaling. J Cell Biol 217, 517-526, doi:10.1083/jcb.201706027 (2018).


  30. Mitteldorf, J. An Incipient Revolution in the Testing of Anti-aging Strategies. Biochemistry (Mosc) 83, 1517-1523, doi:10.1134/S000629791812009X (2018).


  31. Mitteldorf, J. Can Aging be Programmed? Biochemistry (Mosc) 83, 1524-1533, doi:10.1134/S0006297918120106 (2018).


  32. Mei, Long, Zhan, Cheng & Zhang, Eric Erquan*. In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters. J Vis Exp, doi:10.3791/56765 (2018).


  33. Mei, Long, Fan, Yanyan, Lv, Xiaohua, Welsh, David K, Zhan, Cheng & Zhang, Eric Erquan*. Long-term in vivo recording of circadian rhythms in brains of freely moving mice. Proc Natl Acad Sci U S A 115, 4276-4281, doi:10.1073/pnas.1717735115 (2018).


  34. Ma, Xueyan, Li, Peixue, Chen, Peihao, Li, Jinhui, Huang, Hongling, Wang, Chao, Li, Wenjing, Ding, Jianping, Zhao, Yun, Yu, Fa-Xing, Qi, Xiangbing* & Zhang, Lei*. Staurosporine targets the Hippo pathway to inhibit cell growth. J Mol Cell Biol 10, 267-269, doi:10.1093/jmcb/mjy016 (2018).


  35. Luo, Yu-Xi, Han, Yong-Feng, Zhao, Qiu-Yuan, Du, Jin-Lu, Dou, Kun, Li, Lin, Chen, She & He, Xin-Jian*. Sumoylation of SUVR2 contributes to its role in transcriptional gene silencing. Sci China Life Sci 61, 235-243, doi:10.1007/s11427-017-9146-2 (2018).


  36. Lu, Shan, Cao, Yong, Fan, Sheng-Bo, Chen, Zhen-Lin, Fang, Run-Qian, He, Si-Min & Dong, Meng-Qiu*. Mapping disulfide bonds from sub-micrograms of purified proteins or micrograms of complex protein mixtures. Biophys Rep 4, 68-81, doi:10.1007/s41048-018-0050-6 (2018).


  37. Liu, Xiao-Man, Yamasaki, Akinori, Du, Xiao-Min, Coffman, Valerie C, Ohsumi, Yoshinori, Nakatogawa, Hitoshi, Wu, Jian-Qiu, Noda, Nobuo N* & Du, Li-Lin*. Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein. Elife 7, doi:10.7554/eLife.41237 (2018).


  38. Liu, Wang, Zhou, Yan, Peng, Tao, Zhou, Ping, Ding, Xiaojun, Li, Zilin, Zhong, Haoyu, Xu, Yue, Chen, She, Hang, Howard C* & Shao, Feng*. N(epsilon)-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function. Nat Microbiol 3, 996-1009, doi:10.1038/s41564-018-0215-6 (2018).


  39. Liu, Jinchao, Li, Meijiao, Li, Lin, Chen, She & Wang, Xiaochen*. Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation. J Cell Biol 217, 347-360, doi:10.1083/jcb.201705116 (2018).


  40. Liu, Chenxuan, Xu, Guangwei, Gao, Zhenchao, Zhou, Zhongmin, Guo, Guilan, Li, Dan, Jing, Zhiyi, Sui, Jianhua & Li, Wenhui*. The p.Ser267Phe variant of sodium taurocholate cotransporting polypeptide (NTCP) supports HBV infection with a low efficiency. Virology 522, 168-176, doi:10.1016/j.virol.2018.07.006 (2018).


  41. Lin, Rui, Wang, Ruiyu, Yuan, Jing, Feng, Qiru, Zhou, Youtong, Zeng, Shaoqun, Ren, Miao, Jiang, Siqi, Ni, Hong, Zhou, Can, Gong, Hui* & Luo, Minmin*. Cell-type-specific and projection-specific brain-wide reconstruction of single neurons. Nat Methods 15, 1033-1036, doi:10.1038/s41592-018-0184-y (2018).


  42. Lin, Rui*, Li, Yi & Luo, Minmin. A Neural Circuit Driving Maternal Behaviors. Neuron 98, 6-8, doi:10.1016/j.neuron.2018.03.025 (2018).


  43. Lin, Rui, Feng, Qiru, Li, Peng, Zhou, Ping, Wang, Ruiyu, Liu, Zhe, Wang, Zhiqiang, Qi, Xiangbing, Tang, Nan, Shao, Feng & Luo, Minmin*. A hybridization-chain-reaction-based method for amplifying immunosignals. Nat Methods 15, 275-278, doi:10.1038/nmeth.4611 (2018).


  44. Li, Yi, Zeng, Jiawei, Zhang, Juen, Yue, Chenyu, Zhong, Weixin, Liu, Zhixiang, Feng, Qiru & Luo, Minmin*. Hypothalamic Circuits for Predation and Evasion. Neuron 97, 911-924 e915, doi:10.1016/j.neuron.2018.01.005 (2018).


  45. Li, Jiao, Wang, Zheng, Chu, Qiqi, Jiang, Kewu, Li, Juan & Tang, Nan*. The Strength of Mechanical Forces Determines the Differentiation of Alveolar Epithelial Cells. Dev Cell 44, 297-312 e295, doi:10.1016/j.devcel.2018.01.008 (2018).


  46. Li, Jiao & Tang, Nan*. May the Force Be with You. Dev Cell 47, 673-674, doi:10.1016/j.devcel.2018.11.041 (2018).


  47. Jiang, W., Zhao, S., Shen, J., Guo, L., Sun, Y., Zhu, Y., Ma, Z., Zhang, X., Hu, Y., Xiao, W., Li, K., Li, S., Zhou, L., Huang, L., Lu, Z., Feng, Y., Xiao, J., Zhang, E. E., Yang, L. & Wan, R. The MiR-135b-BMAL1-YY1 loop disturbs pancreatic clockwork to promote tumourigenesis and chemoresistance. Cell Death Dis 9, 149, doi:10.1038/s41419-017-0233-y (2018).


  48. Jiang, Kewu, Tang, Zan, Li, Juan, Wang, Fengchao & Tang, Nan*. Anxa4 mediated airway progenitor cell migration promotes distal epithelial cell fate specification. Sci Rep 8, 14344, doi:10.1038/s41598-018-32494-z (2018).


  49. Hu, Zexi#, Hu, Yong#, Liu, Xicheng, Xi, Rongwen, Zhang, Aiqun, Liu, Deruo, Xie, Qiang & Chen, Liang*. Correction: Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor. Oncotarget 9, 35283, doi:10.18632/oncotarget.26252 (2018).


  50. Hou, Weijie*, Ren, Yan, Zhang, Zhenhua, Sun, Huan, Ma, Yongfen & Yan, Bo. Novel quinazoline derivatives bearing various 6-benzamide moieties as highly selective and potent EGFR inhibitors. Bioorg Med Chem 26, 1740-1750, doi:10.1016/j.bmc.2018.02.022 (2018).


  51. Hong, Yu, Lu, Guangqing, Duan, Jinzhi, Liu, Wenjing & Zhang, Yu*. Comparison and optimization of CRISPR/dCas9/gRNA genome-labeling systems for live cell imaging. Genome Biol 19, 39, doi:10.1186/s13059-018-1413-5 (2018).


  52. He, Sudan* & Wang, Xiaodong*. RIP kinases as modulators of inflammation and immunity. Nat Immunol 19, 912-922, doi:10.1038/s41590-018-0188-x (2018).


  53. Gao, Lei, Jiang, Yonghua, Mu, Libing, Liu, Yanbin, Wang, Fengchao, Wang, Peng, Zhang, Aiqun, Tang, Nan, Chen, Ting, Luo, Minmin, Yu, Lei, Gao, Shaorong* & Chen, Liang*. Author Correction: Efficient Generation of Mice with Consistent Transgene Expression by FEEST. Sci Rep 8, 15259, doi:10.1038/s41598-018-32184-w (2018).


  54. Duan, Jinzhi, Lu, Guangqing, Hong, Yu, Hu, Qingtao, Mai, Xueying, Guo, Jing, Si, Xiaofang, Wang, Fengchao & Zhang, Yu*. Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice. Genome Biol 19, 192, doi:10.1186/s13059-018-1530-1 (2018).


  55. Ding, Jingjin* & Shao, Feng*. Growing a gasdermin pore in membranes of pyroptotic cells. EMBO J 37, doi:10.15252/embj.2018100067 (2018).


  56. Chen, Jun, Xu, Na, Wang, Chenhui, Huang, Pin, Huang, Huanwei, Jin, Zhen, Yu, Zhongsheng, Cai, Tao, Jiao, Renjie & Xi, Rongwen*. Transient Scute activation via a self-stimulatory loop directs enteroendocrine cell pair specification from self-renewing intestinal stem cells. Nat Cell Biol 20, 152-161, doi:10.1038/s41556-017-0020-0 (2018).


  57. Chen, Jun, Xu, Na, Wang, Chenhui, Huang, Pin, Huang, Huanwei, Jin, Zhen, Yu, Zhongsheng, Cai, Tao, Jiao, Renjie & Xi, Rongwen*. Author Correction: Transient Scute activation via a self-stimulatory loop directs enteroendocrine cell pair specification from self-renewing intestinal stem cells. Nat Cell Biol 20, 991, doi:10.1038/s41556-018-0053-z (2018).



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