| |
 |
|
Jianmin Zhou, Ph.D.
Associate Investigator, NIBS, Beijing, China
Phone：86-10-80728594
Fax： 86-10-80726687
E-mail： zhoujianmin@nibs.ac.cn
|
Education:
|
1994 |
Ph.D., Horticulture, Purdue University |
|
1987 |
M.S., Institute of Genetics, Academia Sinica, Beijing, China |
|
1984 |
B.S., Department of Biology, Sichuan University, Chengdu, China |
Professional Experience:
|
2004 – present |
Associate Investigator, National Institute of Biological Sciences, Beijing |
|
2002 – 2005 |
Associate Professor of Plant Pathology, Kansas State University |
|
1997 – 2002 |
Assistant Professor of Plant Pathology, Kansas State University |
|
1994 – 1997 |
Post-Doctoral Associate, Purdue University |
|
9/89 – 5/94 |
Doctoral Research Assistant, Purdue University |
|
1987 – 1989 |
Research Associate, Institute of Genetics, Academia Sinica |
|
1984 – 1987 |
Master’s Research Assistant, Institute of Genetics, Academia Sinica |
OTHER PROFESSIONAL ACTIVITIES
Editor, Molecular Plant, 2007-present
Member, The Plant Journal Advisory Board., 2004-2007
Panelist, NIH HIBP study section, 2005.
Panelist, USDA NRI Plant Genetic Mechanism Program, 2003
Manuscript Reviewers: Cell Host & Microbe, Plant Cell, Plant Journal, Plant Physiology, MPMI, Mol Plant Pathology, Plant Mol Biol, Trends in Plant Science, Molecular Plant, Physiological and Molecular Plant Pathology.
Ad-hoc Reviewers: NSF, USDA NRI, USDA BARD.
RESEARCH INTERESTS
My primary interest is centered on the mechanisms in plant-pathogen interactions. Current research involves Arabidopsis nonhost resistance mechanisms, early signaling in bacterial pathogenesis, and disease-response gene regulation in plants.
Publications:
|
1. |
Na Zong, Tingting Xiang, Yan Zou, Jijie Chai, and Jian-Min Zhou (2008). Blocking and triggering of plant immunity by Pseudomonas syringae effector AvrPto. Plant Signaling & Behavior, 3: 583-585. |
|
2. |
Jian-Min Zhou and Jijie Chai (2008). Plant pathogenic bacterial effectors subdue host responses. Current Opinion in Microbiology, 11: 179-185 (Invited Review). |
|
3. |
Huamin Chen, Yan Zou, Yulei Shang, Huiqiong Lin, Yujing Wang, Run Cai, Xiaoyan Tang, and Jian-Min Zhou (2008). Firefly luciferase complementation imaging assay for protein-protein interactions in plants. Plant Physiol. 146: 368-376. |
|
4. |
Linjie Chen, Huayi Wang, Jie Zhang, Lichuan Gu, Niu Huang, Jian-Min Zhou, and Jijie Chai (2008). Structural basis for the catalytic mechanism of phosphothreonine lyase. Nat Struct Mol Biol, 15, 101-102. |
|
5. |
Tingting Xiang, Na Zong, Yan Zou, Yong Wu, Jie Zhang, Weiman Xing, Yan Li, Xiaoyan Tang, Lihuang Zhu, Jijie Chai, and Jian-Min Zhou (2008). Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases. Curr Biol, 18, 74-80. |
|
6. |
Weiman Xing, Yan Zou, Qun Liu, Jianing Liu, Xi Luo, Qingqiu Huang, She Chen, Lihuang Zhu, Ruchang Bi, Quan Hao, Jia-Wei Wu, Jian-Min Zhou, and Jijie Chai (2007). Structural basis for activation of plant immunity by bacterial effector protein AvrPto. Nature, 449, 243-247. |
|
7. |
Jie Zhang, Feng Shao, Yan Li, Haitao Cui, Linjie Chen, Hongtao Li, Yan Zou, Chengzu Long, Lefu Lan, Jijie Chai, She Chen, Xiaoyan Tang, and Jian-Min Zhou (2007). A Pseudomonas syringae Effector Inactivates MAPKs to Suppress PAMP-Induced Immunity. Cell Host & Microbe, 1,175-185. |
|
8. |
Hongtao Li, Hao Xu, Yan Zhou, Jie Zhang, Chengzu Long, Shuqin Li, She Chen, Jian-Min Zhou, Feng Shao (2007). The phosphothreonine lyase activity of a bacterial type III effector family. Science 315: 1000-1003. |
|
9. |
Yanmei Xiao, Lefu Lan, Chuntao Yin, Xin Deng, Doug W. Baker, Jian-Min Zhou, Xiaoyan Tang (2007). Two-component sensor RhpS promotes induction of Pseudomonas syringae type III secretion system by repressing negative regulator RhpR. MPMI, 20: 223-234. |
|
10. |
Lefu Lan, Xin Deng, Yanmei Xiao, Jian-Min Zhou, Xiaoyan Tang (2007). Mutation of Lon protease differentially affects Pseudomonas syringae TTSS gene expression in rich and minimal media and reduces pathogenicity. MPMI, 20: 682-696. |
|
11. |
Lefu Lan, Xing Deng, Jian-Min Zhou, and Xiaoyan Tang (2006). Genome-wide gene expression analysis of Pseudomonas syringae pv. tomato DC3000 reveals overlapping and distinct pathways regulated by hrpL and hrpRS. MPMI 19: 976-987. |
|
12. |
Yulei Shang, Xinyan Li, Haitao Cui, Ping He, Roger Thilmony, Satya Chintamanani, Julie Zwiesler-Vollick, Suresh Gopalan, Xiaoyan Tang, and Jian-Min Zhou (2006). RAR1, a central player in plant immunity, is targeted by Pseudomonas syringae effector AvrB. PNAS (track II), 103: 19200-19205. |
|
13. |
Xiaoyan Tang and Jian-Min Zhou (2006). Regulation of the type III secretion system in phytopathogenic bacteria. MPMI, 19, 1159-1166. (review). |
|
14. |
Alexandra. Robert-Seilaniantz, Libo Shan, Jian-Min Zhou, and Xiaoyan Tang (2006). The Pseudomonas syringae pv. tomato DC3000 Type III Effector HopF2 Has a Putative Myristoylation Site Required for Its Avirulence and Virulence Functions. MPMI, 19: 130-138. |
|
15. |
Xinyan Li, Huiqiong Lin, Weiguo Zhang, Yan Zou, Jie Zhang, Xiaoyan Tang, and Jian-Min Zhou (2005). Flagellin induces innate immunity in nonhost interactions that is suppressed by Pseudomonas syringae effectors. PNAS (track II), 102: 12990-12995. |
|
16. |
Fangming Xiao, S. Mark Goodwin, Yanmei Xiao, Zhaoyu Sun, Douglas Baker, Xiaoyan Tang, Matthew A. Jenks, and Jian-Min Zhou (2004) Arabidopsis CYP86A2 represses Pseudomonas syringae type III genes and is required for cuticle development. EMBO J., 23: 2903-2913. |
|
17. |
Thara K. Venkatappa, Alexander R. Seilaniantz, Youping Deng, Yinghua Dong, Yinong Yang, Xiaoyan Tang, and Jian-Min Zhou (2004) Tobacco Genes Induced by the Bacterial Effector Protein AvrPto. MPMI, 17, 1139-1145. |
|
18. |
Ping He, Satya Chintamanani, Zhongying Chen, Lihuang Zhu, Barbara N. Kunkel, James R. Alfano, Xiaoyan Tang, and Jian-Min Zhou (2004). Activation of a COI1-dependent pathway in Arabidopsis by Pseudomonas syringae type III effectors and coronatine. The Plant Journal, 37, 589-602. |
|
19. |
Li Kang, Jianxiong Li, Tiehan Zhao, Fangming Xiao, Xiaoyan Tang, Roger Thilmony, ShengYang He, and Jian-Min Zhou (2003). Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence. PNAS (track II), 100, 3519-3524. |
|
20. |
Jian-Min Zhou and Xiaoyan Tang (2002). Plant disease resistance genes in gene-for-gene resistance and general resistance. In: Andrew J. Wood ed. Biochemical and Molecular Responses of Plants to the Environment, Biochemical & Molecular Responses of Plants to the Environment. Research Signpost, Trivandrum India. pp127. ISBN: 81-7736-167-8. |
|
21. |
Ping He, Bernd Friebe, Bikram Gill, and Jian-Min Zhou (2003). Allopolyploidy alters gene expression in the highly stable hexaploid wheat. Plant Molecular Biology, 52, 401-414. |
|
22. |
Thara Venkatappa, John Fellers, and Jian-Min Zhou (2003). In planta induced genes of Puccinia triticina. Molecular Plant Pathology, 4, 51-56. |
|
23. |
Fangming Xiao, Ming Lu, Tiehan Zhao, Xiaoyan Tang, and Jian-Min Zhou (2003). Pto mutants differentially activate Prf-dependent, AvrPto-independent resistance and gene-for-gene resistance. Plant Physiology, 131, 1239-1249. |
|
24. |
Jianxiong Li, Libo Shan, Jian-Min Zhou, and Xiaoyan Tang (2002). Overexpression of Pto induces a salicylate-independent cell death but inhibits necrotic lesions caused by salicylate deficiency in tomato plants. MPMI, 15, 654-661. |
|
25. |
Fang-Ming Xiao, Xiaoyan Tang, and Jian-Min Zhou (2001). Expression of 35S::Pto globally activates defense gene expression in tomato plants. Plant Physiology, 126, 1637-1645. |
|
26. |
Ping He, Randall F. Warren, Libo Shan, Tiehan Zhao, Lihuang Zhu, Xiaoyan Tang, and Jian-Min Zhou (2001). Overexpression of Pti5 potentiates pathogen-induced defense gene expression in tomato. MPMI 14, 1453-1457. |
|
27. |
Ming Lu, Xiaoyan Tang, and Jian-Min Zhou. (2001) Arabidopsis NHO1 is required for general resistance against Pseudomonas bacteria. Plant Cell, 13, 437-447. |
|
28. |
Libo Shan, Venkatappa Thara, Gregory Martin, Jian-Min Zhou, and Xiaoyan Tang (2000). The Pseudomonas AvrPto protein is differentially recognized by tomato and tobacco and is localized to the plant plasma membrane. Plant Cell, 12, 2323-2338. |
|
29. |
Libo Shan, Ping He, Jian-Min Zhou, and Xiaoyan Tang (2000). A cluster of mutations disrupt the avirulence but not the virulence function of AvrPto. MPMI 13, 592-598. |
|
30. |
Yong-Qiang Gu, Caimei Yang, Venkatappa Thara, Jian-Min Zhou, and Gregory Martin (2000). Pti4 is induced by ethylene and salicylic acid, and its product is phosphorylated by the Pto kinase. Plant Cell 12, 771-785. |
|
31. |
Venkatappa K. Thara, Xiaoyan Tang, Gregory B. Martin, and Jian-Min Zhou (1999). Pseudomonas syringae pv tomato induces the expression of tomato EREBP-like genes Pti4 and Pti5 independent of ethylene, salicylate and jasmonate. Plant J. 20, 475-483. |
|
32. |
Jian-Min Zhou (1999). Signal transduction and pathogen-induced PR gene expression. In: Pathogenesis-related proteins in plants, S.K. Datta and S. Muthukrishnan eds., CRC Press. 195-206. |
|
33. |
Xiaoyan Tang, Mingtang Xie, Young Jin-Kim, Jian-Min Zhou, Daniel F. Klessig, and Gregory B. Martin (1999). Overexpression of Pto Activates Defense Responses and Confers Broad Resistance. Plant Cell 11: 15-30. |
|
34. |
Ying-Tsu Loh, Jian-Min Zhou, and Gregory Martin (1998). The myristylation motif of Pto is not required for disease resistance. Mol. Plant-Microbe Interct. 11, 572-576. |
|
35. |
Ping Xu, Meena Narasimhan, Teresa Samson, Maria Coca, Gyung-Hye Huh, Jian-Min Zhou, Gregory Martin, Paul Hasegawa, and Ray Bressan (1998). A nitrilase-like protein interacts with GCC box DNA-binding proteins involved in ethylene and defense responses. Plant Physiology 118, 867-874. |
|
36. |
Jian-Min Zhou, Xiaoyan Tang, Reid Frederick, and Gregory Martin (1998). Pathogen recognition and signal transduction by the Pto kinase. J. Plant Res. 111, 353-356. |
|
37. |
Jian-Min Zhou, Xiaoyan Tang, and Gregory Martin (1997). The Pto kinase conferring resistance to tomato bacterial speck disease interacts with proteins that bind a cis-element of pathogenesis-related genes. EMBO Journal 16, 3207-3218. |
|
38. |
Yulin Jia, Ying-Tsu Loh, Jian-Min Zhou, and Gregory Martin (1997). Alleles of Pto and Fen occur in bacterial speck-susceptible and fenthion-insensitive tomato lines and encode functional protein kinases. Plant Cell 9, 61-73. |
|
39. |
Angus Murphy, Jian-Min Zhou, Peter B. Goldsbrough, and Lincoln Taiz (1997). Purification and immunological identification of metallothioneins 1 and 2 from Arabidopsis thaliana. Plant Physiology 113, 1293-1301. |
|
40. |
Jianjun Chen, Jian-Min Zhou, and Peter B. Goldsbrough (1997). Characterization of phytochelatin synthase from tomato. Physiologia Plantarum 101, 165-172. |
|
41. |
Martin, G.B., Xiaoyan Tang, Jianmin Zhou, Reid Frederick, Yulin Jia, and Ying-Tsu Loh (1996). Signal recognition and transduction in bacterial speck disease resistance of tomato. In: Biology of Plant-Microbe Interactions, G. Stacey et al. eds. (International Society for Molecular-Microbe Interactions, St. Paul, Minnesota). |
|
42. |
Martin, G.B., Reid Frederick, Roger L. Thilmony, and Jianmin Zhou (1996). Signal transduction events involved in plant disease resistance. In: Molecular Aspects of Pathogenicity and Resistance: Requirement for Signal Transduction, D. Mills, H. Kunoh, N. T. Keen and S. Mayama eds. U.S./Japan Seminar Series Proceedings, pp. 163-176. |
|
43. |
Xiaoyan Tang, Reid D. Frederick, Jianmin Zhou, Dennis A. Halterman, Yulin Jia, and Gregory B. Martin (1996). Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase. Science 274, 2060-2063. |
|
44. |
Jianmin Zhou, Ying-Tsu Loh, Ray Bressan, and Gregory Martin (1995). The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response. Cell 83, 925-935. |
|
45. |
Jianmin Zhou and Peter B. Goldsbrough (1995). Structure, organization and expression of Arabidopsis metallothionein gene family. Mol. Gen. Genet. 248, 318-328. |
|
46. |
Jianmin Zhou and Peter B. Goldsbrough (1994). Functional homologues of animal and fungal metallothionein genes from Arabidopsis. Plant Cell 6, 875-884. |
|
47. |
Jianmin Zhou and Peter B. Goldsbrough (1993). An Arabidopsis gene with homology to glutathione s-transferases is regulated by ethylene. Plant Molecular Biology 22, 517-523. |
|
48. |
Jiaping Zhou, Jianmin Zhou, Sixin Liang, He Huang, Long Pang, and Yinxian Jiao (1990). Cell selection of the tobacco mutant resistant to black shank disease. Acta Genetica Sinica 17(3), 180-188. |
|
|
